SELECT 
  cscart_product_prices.product_id, 
  MIN(
    IF(
      cscart_product_prices.percentage_discount = 0, 
      cscart_product_prices.price, 
      cscart_product_prices.price - (
        cscart_product_prices.price * cscart_product_prices.percentage_discount
      )/ 100
    )
  ) AS price 
FROM 
  cscart_product_prices 
WHERE 
  cscart_product_prices.product_id IN (
    145, 117, 113, 157, 68, 29, 6, 8, 14, 9, 
    10, 19, 21, 50, 51, 49, 48, 54, 153, 164, 
    248, 65, 64, 63
  ) 
  AND cscart_product_prices.lower_limit = 1 
  AND cscart_product_prices.usergroup_id IN (0, 1) 
GROUP BY 
  cscart_product_prices.product_id

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "60.41"
    },
    "grouping_operation": {
      "using_filesort": false,
      "table": {
        "table_name": "cscart_product_prices",
        "access_type": "range",
        "possible_keys": [
          "usergroup",
          "product_id",
          "lower_limit",
          "usergroup_id"
        ],
        "key": "product_id",
        "used_key_parts": [
          "product_id"
        ],
        "key_length": "3",
        "rows_examined_per_scan": 26,
        "rows_produced_per_join": 5,
        "filtered": "19.67",
        "index_condition": "(`danishecarter_latest`.`cscart_product_prices`.`product_id` in (145,117,113,157,68,29,6,8,14,9,10,19,21,50,51,49,48,54,153,164,248,65,64,63))",
        "cost_info": {
          "read_cost": "59.39",
          "eval_cost": "1.02",
          "prefix_cost": "60.41",
          "data_read_per_join": "122"
        },
        "used_columns": [
          "product_id",
          "price",
          "percentage_discount",
          "lower_limit",
          "usergroup_id"
        ],
        "attached_condition": "((`danishecarter_latest`.`cscart_product_prices`.`lower_limit` = 1) and (`danishecarter_latest`.`cscart_product_prices`.`usergroup_id` in (0,1)))"
      }
    }
  }
}

Result

product_id price
6 329.99000000
8 849.99000000
9 999.99000000
10 1199.99000000
14 499.99000000
19 79.99000000
21 29.99000000
29 199.95000000
48 180.00000000
49 120.00000000
50 220.00000000
51 180.00000000
54 269.00000000
63 189.95000000
64 189.95000000
65 99.95000000
68 799.99000000
113 449.99000000
117 729.99000000
145 79.99000000
153 49.99000000
157 499.00000000
164 249.99000000
248 372.27000000